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In a note from Dr Maycock to Miss Long, the need to tell patients that they were at risk of contracting hepatitis via transfusion was noted.

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In a letter from J H Keidan Solicitors to Miss Long, the need to tell patients they were at risk was advised by solicitors.

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It was noted in MacCallum's Homologous Serum Hepatitis Proceedings of the Royal Society of Medicine that pooling plasma from a larger pool of donors would increase the risk of contracting hepatitis.

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Dr Maycock was concerned that a legal case regarding a lady that had died from hepatitis-related transfusion would lead to the plasma production being stopped.

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Dr Maycock did not believe there would be a strong case against the Blood Transfusion Service regarding a case involving hepatitis related transfusion, however was concerned that if litigation did take place, it could shut off the supply of plasma.

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The post-mortem of a woman affected by transfusion-related jaundice returned a verdict of misadventure.

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Large pool plasma filtration was abandoned due to the prevalence of homologous serum jaundice.

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By 1975, two years after Hepatitis A was identified, there was a test for both Hepatitis A and Hepatitis B.

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US studies showed that serum hepatitis caused death at a rate of approximately 1 in every 150 transfusions in the US in people over the age of 40. US Studies showed the mortality rate in late middle age of those infected could be as high as 40%.

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Update on the expert groups ahead of the preliminary hearings

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Inquiry publishes report by the Statistics Expert Group

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Further instruction letter to Psychosocial expert group published

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"The Sunday Telegraph" reported that a post-mortem carried out on a man with haemophilia found the vCJD prion in his spleen, which prompted an update being urgently sent to people with bleeding disorders.

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The chief medical officers of each of the four nations responded to a request to approve the framework for the management of possible exposures to CJD through medical procedures.

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A fourth case of vCJD transmission was associated with blood transfusion and was reported to the press.

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It was confirmed that a post-mortem carried out on a man with haemophilia found the vCJD prion in his spleen. He did not die of vCJD; nor was it present in the brain. The probability was that he had been infected and that the likeliest cause was his treatment with plasma product.

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The CJD Incidents Panel wrote to those responsible for tracing vCJD-implicated plasma batches setting out tables of implicated batch numbers.

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A second case of transfusion-related vCJD was reported in July 2004.

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People with a bleeding disorder were informed by their haemophilia centre and given an opportunity to discuss the implications and to find out if they had received an implicated batch if they wished.

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Alan Milburn, Secretary of State for Health, announced further details of the compensation scheme.

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