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The full report for the multi-centre study on non-A non-B Hepatitis surrogate screening was eventually completed in April 1990.

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Anti-HCV testing was to begin on 1 September 1991.

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In the mid to late 1980s in the US, the incidence of non-A non-B Hepatitis was 7-12%.

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The "line to take" included "UK blood is still considered one of the safest in the world, and we continue to investigate ways of making it safer still" and "The prevalence of Hepatitis C in the population in this country has not been established, nor has the role of blood in its transmission."

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Professor John Cash asked Dr Ginger Rosenberg at Chiron for access in due course to antibody testing kits for evaluation purposes.

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Robert Panton requested funding for the pilot study.

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Ortho organised a meeting in London with representatives from both the English and Scottish blood services to look at the preliminary UKBTS data.

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It was "important that the UK Blood Transfusion Services should act in unison on this subject" of HCV testing.

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Dr Lloyd reiterated his concern that the UK was "dragging its feet over testing" and was running the risk of "accepting the lowest common denominator" approach.

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Dr Boulton insisted that the screening of donors for HCV antibodies should be introduced at the earliest possible opportunity.

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At a meeting of the SNBTS directors Dr Gunson reported the agreement to conduct a UK study, with 1,000 samples to be sent from the UK to Chiron for blind testing.

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On 7 January 1991, at a meeting of the NBTS/SNBTS Liaison Committee it was reported that no decision had been taken by the Department of Health on the implementation or funding of anti-HCV testing.

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Professor Cash insisted that HCV testing be discussed.

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Scotland were under pressure from the SNBTS to fund the introduction of additional virological testing for HCV, but wanted to know what the UK planned to do first.

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An HCV test would be available towards the end of 1989, but there was a great deal of work to do regarding manufacturing and trials to get to that point.

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The anticipated commencement date for the Ortho and Abbott 1&2 tests was 1 July 1991.

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Professor Cash asked for "some idea of the current time schedule to the point of full marketing in the UK for full donation testing."

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Dr Gunson and Dr Perry had argued that there was already sufficient data for ACVSB to recommend to ministers the introduction of a first-generation Hepatitis C donation screening as soon as possible, but their views were rejected.

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Professor Cash suggested that the evaluation of second-generation tests might be modified to accommodate the screening programme in Newcastle.

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Professor Cash noted that Dr Gunson conveyed his concern that the Department of Health had still not decided on a start date, and it now seemed the earliest possible date would be May or June 1991.

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