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Dr Frank Boulton stated to the Penrose Inquiry "Peter Jones and many like him were reluctant to... go back ten years or so to the style of treatments usually only cryoprecipitate or small pooled products which would reduce the dosage that children could get and return them to a risk of getting permanent joint damage from their early years".

Published on: 30 September, 2024

Dr Boulton felt that Dr Jones was "still being somewhat less than cautious" with regard to his attitude towards the risk of AIDS.

Published on: 30 September, 2024

Commercial concentrates continued to be the mainstay of treatment at the Newcastle Haemophilia Centre in 1983.

Published on: 30 September, 2024

Commercial concentrates continued to be the mainstay of treatment at the Newcastle Haemophilia Centre in 1984.

Published on: 30 September, 2024

Dr Jones formed the view in the course of November 1984 that there should be a change to heat-treated Factor 8 and took steps to secure the regional health authority's agreement to that change.

Published on: 30 September, 2024

Dr Jones did not take steps to recall existing unheated product from patients: instead they were told to use up their present stocks and that the switch would be made when they came back for new supplies for their home therapy.

Published on: 30 September, 2024

Dr Jones had checked with representatives of the three companies (Armour, Cutter, and Alpha) supplying concentrates to the Centre who had all agreed to take back present stocks of non-heat-treated material without any financial consequences to the Health Authority.

Published on: 30 September, 2024

Terence McStay was the second patient to die of AIDS in the UK and a patient at the Newcastle Centre. He returned to his home in Glasgow shortly after he was diagnosed, and died on 3 November 1984.

Published on: 30 September, 2024

In the Daily Mail, it was reported that "Terence McStay went through seven months of hell before he died."

Published on: 30 September, 2024

In the Guardian, it was reported that Terence McStay had died after receiving a blood transfusion at Newcastle hospital.

Published on: 30 September, 2024

In a journal article in the Lancet, it was reported that "If the UK had been self-sufficient in factor concentrates, and these results had been replicated, generally they suggest that over 80% of the infections which occurred would have been spared".

Published on: 30 September, 2024

In Glasgow Royal Infirmary, the 77 patients whose blood was tested for HIV as part of a study were not told that these tests were taking place.

Published on: 30 September, 2024

Figures relating to the annual consumption of commercial factor concentrate at different haemophilia centres between 1976 and 1994. Also included are the factor types, product names, haemophilia type, number of units and volume amounts.

Published on: 30 September, 2024

At a Committee on Safety of Medicines Sub-Committee on Biological Products meeting, it was stated that the cause of AIDS was unknown. It was postulated that a new agent may have beeen responsible, but repeated exposure to, or reactivation of, known agents, (e.g. CMV, EBV) may have beeen involved.

Published on: 30 September, 2024

The UKHCDO recommended at the end of the 1983 meeting that patients did not switch from concentrates to cryo.

Published on: 30 September, 2024

Professor Franklin described in a letter how he and Professor Hill took the view that patients should have continuity in their factor product and given how erratic the NHS supply was it was better to keep them on commercial Factor VIII than switch between the two when NHS product was available.

Published on: 30 September, 2024

Dr Ala advised the West Midlands Working Party meeting - through letter - that cryoprecipitate was "probably a safer product than Factor VIII concentrate in respect of transmission of AIDS".

Published on: 30 September, 2024

The Working Party meeting did not result in any change of approach in regards to cryoprecipitate.

Published on: 30 September, 2024

The Queen Elizabeth Hospital return for 1983 showed some treatment with cryoprecipitate in hospital but predominantly treatment with NHS concentrate and Factorate in both hospital and home settings.

Published on: 30 September, 2024

The return for 1984 showed for the Queen Elizabeth Hospital that there was predominantly treatment with NHS concentrate and Factorate in both hospital and home settings.

Published on: 30 September, 2024

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