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Dr Lane's account of 1981 was one of his battles to secure a commitment from the government to redevelop BPL, and to fund the improvements necessary following an adverse Medicines' Inspectorate report.

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Dr James Smith proposed to Dr Lane some first outline proposals for programmes to research tackling the transmission of viruses by coagulation factor concentrates. This proposal, according to Dr Lane, marked "the start of a move towards a viral inactivation programme."

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It was apparent that there was some resistance by some clinicians to the use of heat-treated product.

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Transfusion directors in the Joint Steering Committee on Blood Products Production increased the goal of 250,000 donations in March 1973 to 275,000 in June and July 1973.

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Dr Arblaster reported 'practical difficulties' during a prophylaxis trial at Treloar's.

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In a meeting it was stressed that Dr Bigg's paper indicated in five years time there may be a need for more material, haemophilia centre directors and transfusion directors approved the contents of the paper and recommended that this document be used as the basis for planning the future requirements for Factor 8 in the United Kingdom.

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At a joint meeting of haemophilia centre directors and blood transfusion directors, it was stressed that home therapy was becoming more accepted and widespread and was improving patients' lives. Some directors of haemophilia centres were buying commercial concentrates for use in home therapy

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The change to single plasma packs proved efficient in saving time and resources at regional transfusion centres.

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Planning was eventually under way for a new building to constitute BPL at Elstree.

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The Policy Steering Group proposed a new laboratory be built at BPL at a cost of £21.1 million spread over the years 1982/83 to 1985/86.

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In a note to Dr Maycock, Dr Ellis expressed that expansion to producing 25 million international units of Factor 8 per year would cause a serious overcrowding of facilities, unless some additional building work was done.

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A study by Dr Rosemary Biggs suggested that the theoretical danger of exposure to infection increased with the number of donations contributing to the treatment material used. However, severely affected and multi-transfused patients were not found to have a high incidence of clinical illness associated with jaundice, which suggested that large pools might contain Hepatitis B antibody which might reduce infectivity.

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A complaint to a police force in Wales was processed.

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Jane Hutt wrote to Haydn Lewis stating that the Irish compensation scheme was being set up following evidence of negligence by the Irish Blood Service, but "that blood services in the UK have not been found to be similarly at fault."

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Revered Tanner sent a petition to the Prime Minister describing the Government's stance as both illogical and morally indefensible.

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Lord Warner advised Lord Morris that the report on self-sufficiency was not yet completed.

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In a letter from Gwilym Jones, the Parliamentary Under-Secretary at the Welsh Office, to the father of a son infected with Hepatitis C it was stated that the Government made no plans to make payments to individuals with Hepatitis C.

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Planning was under way for a new building to constitute BPL at Elstree. A plasma supply target of 435,000 kilograms, including this element for cryoprecipitate production, was broadly maintained with a growing consensus that demand for Factor 8 would increase in the region to around 100 million international units.

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A plasma supply target of 435,000 kilograms was broadly maintained, and although estimates thereafter continued to increase, there was a growing consensus that demand for Factor 8 would increase to the region of 100 million international units. The increases in estimated needs were by this time gradual compared to those that came before.

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Counsel's note to the Inquiry on Collective Responsibility/Safe Space for Policy-Making.

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