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Dr Lane reported that "a research project into the development of coagulation factor concentrates with reduced risk of hepatitis transmission, was an appropriate case for central funding."

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Dr Lane in his draft proof of evidence for the HIV Haemophilia Litigation, wrote "The documentation I have discussed above indicates our intention to define a heat treatment process capable of full virus inactivation, probably requiring more severe heating than was currently recognised."

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There were discussions at BPL about the degree of success commercial firms had in reducing hepatitis transmission, and answers being sought to questions about the safety and efficacy of those heat-treated concentrates which were being developed elsewhere.

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The "Proposal to Develop a 'Hepatitis-Safe' Factor VIII Concentrate" noted that "NANBH causes increasing concern, less on account of its acute effects (although deaths have been reported) than because of its association with chronic active hepatitis in later life", and that AIDS was "not yet proven to be of viral origin, but this is strongly presumed."

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John Horam requested a brief round-up of the current issues on blood product issues and for advice on whether any amendments should be made to the proposed response to the Haemophilia Society's letter seeking financial assistance for people with haemophilia infected with Hepatitis C.

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A background note suggested that it might take 20 to 30 years to develop cirrhosis and that the majority of those years would be "trouble free in terms of ill health and only a small percentage will actually die of liver disease."

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A minute was sent to Dr Graham Winyard "expressing concern that while SoS accepts that the Government could not afford a large compensation package, he feels that a small hardship fund like the MacFarlane Trust would be possible. Officials are concerned that significant funds would need to be diverted from patient care to fund it and that Treasury remain fundamentally opposed."

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Amidst HIV litigation claims issued against Scottish health boards, the Scottish National Blood Transfusion Service and the Secretary of State for Scotland, defences were filed on behalf of Lothian Health Board and Scottish National Blood Transfusion Service.

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In preparation for a meeting with the Minister of Health, Vicki King sent a draft speech on Hepatitis C for the Adjournment Debate to Jane Colman._

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A draft speech on Hepatitis C prepared by officials for the Parliament Adjournment Debate asserted that: "The technology to make blood products free from hepatitis C in sufficient quantities to treat all haemophiliacs in the UK was simply not possible prior to 1985. Once it was the NHS introduced it."

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There was a delay in officials providing the Secretary of State with the information which he had requested due to issues relating to the emergence of variant Creutzfeldt-Jakob disease, due to a need to complete examinations of the issues and a need to speak to colleagues about the best way to move forward.

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Frank Dobson agreed to consider the Haemophilia Society's points most carefully and said that he would write shortly.

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Concerns were raised at a meeting between the Haemophilia Society and Department of Health that access to recombinant Factor 8 was not equal.

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In a letter to a Dr Lehane, Dr Maycock stated that all large pool plasma should be replaced with small pool plasma and that the large pool plasma could be diverted to Liverpool so that the small pools could be examined for infectivity.

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The DHSS invested £400,000 in the Protein Fractionation Centre towards the capital costs.

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The Scottish Home and Health Department suggested that there should be a management policy committee covering both the Blood Products Laboratory and the Protein Fractionation Centre to ensure that a common production policy would apply to both laboratories.

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The action plan for January 2007 recorded that ten files of recently located Wellington House documents were to be reviewed, along with 28 files from the Departmental Records Office in Nelson.

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Lord Owen wrote a letter asking about outcomes from the Burgin report but Richard Gutowski noted in a memo that he did not think that the Self-Sufficiency Report had been set up to address Lord Owen's concerns that his papers had been pulped.

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The Department of Health instructed Leigh-Ann Mulcahy to examine the documents returned to the Department of Health by the claimants' solicitors in the HIV litigation and prepare a report.

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Department of Health Report titled 'Getting ahead of the Curve. A strategy for combating infectious diseases (including other aspects of health protection)' (the Donaldson report) was published.

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