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An email from Mike Patrick to Zubeda Seedat confirmed that it was not unlikely given the duration of time that the documents requested in the Freedom of Information request had been destroyed considering the fact that litigation had been settled over 15 years ago.

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Charles Lister and Anita James concluded that, following the discovery that the documents had been destroyed, she would say an audit had been done by a junior official at the Department of Health who no longer worked there.

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Lord Owen wrote a letter asking about outcomes from the Burgin report but Richard Gutowski noted in a memo that he did not think that the Self-Sufficiency Report had been set up to address Lord Owen's concerns that his papers had been pulped.

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Michelle Haywood and William Connon emailed to explore the possibility of further searches of records at archives.

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Records held by the Department of Health were destroyed in the early nineties because they had been given a short destruction date.

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A review was conducted of documentation regarding governmental policy in relation to the safety of blood products.

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Documents held by the claimants' solicitors, Blackett Hart & Pratt Solicitors, in the HIV litigation were returned in the week of 19 May 2006.

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The House of Lords heard how documents that had been disclosed by the Department of Health held by the claimants' solicitors, Blackett Hart & Pratt Solicitors, in the HIV litigation were returned. However, some 600 files were destroyed.

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Anita James showed her notebook which demonstrated the numbers of the missing files.

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Around early 2006 documents held by the claimants' solicitors in the HIV litigation were returned. However, these were copies of the documents rather than the Department of Health's original versions.

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The Scottish Executive released a large number of documents, some of which the Department of Health, in an internal memo, believed would "inevitably be copies of the ones destroyed by DH".

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William Connon instructed that a "definitive list" be compiled showing all sets of documents that were destroyed, when they were destroyed, the circumstances of destruction and "likelihood of the documents which had just been found by the solicitors being copies of some of the destroyed documents." Ministers also instructed that an independent legal expert review the documents returned from the claimants' solicitors in the HIV litigation.

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The Department of Health commissioned an independent legal expert to undertake an initial analysis of the documents that had been returned from the claimants' solicitors in the HIV litigation.

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The parents of a child with haemophilia complained about the lack of recombinant Factor 8, even though the use of the product had been deemed "appropriate on clinical grounds" by the treating clinician.

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HM Customs and Excise decided that recombinant Factor 8 could no longer be considered exempt from VAT because it was not a biological product.

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The tax tribunal gave a detailed judgment when upholding HMCE in deciding that the sale of recombinant was liable to VAT. It recorded findings of fact that recombinant was "now considered as the treatment of choice by most clinicians and by the Haemophilia Society."

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The tax tribunal noted that recombinant had the advantages over blood-derived factor concentrate of being available in an unlimited supply, being a renewable source, and having freedom from blood-borne viral contamination. By comparison, purified plasma derived Factor 8 "might contain low levels of viral contamination."

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A Haemophilia Society Board of Trustees' meeting recorded the unequal availability of recombinant Factor 8 across the UK.

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The chair of the Haemophilia Society wrote to Stephen Dorrell reiterating the uneven availability of recombinant Factor 8 across the UK.

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A panel established by the Board of the Newcastle upon Tyne Hospitals NHS Trust recommended to the Board that "it support the universal availability of recombinant Factor VIII. This recommendation should be conveyed to Health Authorities for funding".

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