Subscribe to Search results

Professor Christopher Ludlum had not been able to recall his views from 1984, however his practice in Edinburgh had stopped using cryoprecipitate for children

Published on:

Professor Christopher Ludlum stated in oral evidence that he had sent samples to Dr Tedder without the patients or their parents knowledge or consent

Published on:

Professor Ludlam wrote to patients inviting hundreds to a meeting to discuss anxieties raised. This was sent to those personally affected but due to a lack of explanation they did not realise. Only a few tens of people turned up to the meeting.

Published on:

Professor Christopher Ludlum recalled that his reasoning for sending the samples were to see if those who had received commercial products were positive and those with Scottish Factor VIII had been negative

Published on:

In his evidence to the Inquiry, Professor Ludlam was asked about a view attributed to him that until the late 1980s the perception was that non-A non-B Hepatitis was a mild non-progressive condition. Professor Ludlam said that this was an "inaccurate summary of my perceptions" and that mid rather than late 1980s would be a more accurate reflection of his views.

Published on:

During the time that Professor Ludlam was working in Cardiff, he recalled Professor Bloom speaking about the Bournemouth hepatitis outbreak of 1974, making the Cardiff director cautious about US concentrates.

Published on:

The geographical area of the Royal Edinburgh Infirmary covered patients in the south of Fife, Kirkcaldy, Dunfermline and most of the Borders.

Published on:

During the 1970s, at the Edinburgh Royal Infirmary, the preferred choice of treatment of Dr Howard Davies was cryoprecipitate, with no commercial concentrates being used.

Published on:

When Dr Ludlam became director in 1980, his approach to treatment was the following: First, he not only made primary treatment from Haemophilia A became Factor 8 concentrate, but also increased the use of factor concentrates as a whole. Second, he increased the number of patients using home treatment.

Published on:

The effect of Professor Ludlam's introduction to factor concentrates was that the local blood transfusion service redirected donor blood plasma from cryoprecipitate production to concentrate manufacture.

Published on:

Towards the end of 1982, concerns arose as to the increased demand and limited supply of commercial treatment following the increase in home treatment. It was therefore necessary for more commercial product to be imported and Dr Ludlam agreed to keep up with the demand.

Published on:

Professor Ludlam described in his oral evidence how in many cases children with Haemophilia A would begin with cryoprecipitate before moving to home treatment.

Published on:

Professor Ludlam described how batch dedication was introduced towards the end of 1984 and it unclear why this was not produced earlier.

Published on:

Professor Ludlam, under counsels questions, amended his earlier submission that in the late 1980s, NANB Hepatitis was believed to be a mild non-progressive condition following the first liver biopsy undertaken in 1985. He corrected this view to say that he was aware of the liver biopsy undertaken in Sheffield in 1978, and thus there was a likelihood of prior knowledge of the condition of NANB Hepatitis earlier than the late 1980s.

Published on:

Professor Ludlam stated that during the 1980s that there was a wide view at the time regarding the seriousness of NANB Hepatitis. The lack of evidence about its progressiveness that resulted in the belief that it's possible it might not be progressive however it became clear that there was a wide range of ways in which it rates at which it did progress between different people.

Published on:

Dr Mitchell recollected that there was no patient at Leicester with mild or moderate Haemophilia A or Haemophilia B, or with von Willebrand disorder who tested positive.

Published on:

Dr Mitchell's policy in relation to adults with severe Haemophilia A was to adhere to one batch of one concentrate as much as possible. It took a year or so to implement this approach.

Published on:

When Dr Mitchell arrived at the Sheffield Centre, the majority of patients on home treatment were receiving commercial concentrate and he did not have the ability to switch them all over to NHS concentrates given the amount received.

Published on:

Whilst there were insufficient supplies so commercial concentrates were used. Dr Mitchell would have used more NHS product if it had been available.

Published on:

The approach at the Sheffield Centre for adults with severe Haemophilia A, was to treat them with NHS concentrates as much as possible.

Published on: