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In his letter to Dr William Maycock, Dr Jack Darnborough rejected the idea of distributing Factor 8 on a supra-regional basis and of RTCs distributing commercial Factor 8 as well as NHS Factor 8 and cryoprecipitate.

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Dr Jack Darnborough agreed to organise the purchase and distribution of commercial Factor 8. He noted one of the reasons for his change of mind as being his knowledge that a haematologist in his region had been purchasing large quantities of commercial Factor 8, costing between £8,000 and £10,000 a year.

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Dr William Maycock convinced Dr Jack Darnborough of the advantages of distributing commercial Factor 8.

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Barry Barber, sales manager at Cutter Laboratories, informed Dr Jack Darnborough (Cambridge RTC), about a request to tender for the next Factor 8 contract.

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Dr Jack Darnborough (Director, East Anglian Blood Transfusion Centre) met with a representative from Cutter Laboratories to discuss the supply of Koate.

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The Yorkshire RTC did not purchase, store or distribute commercial Factor 8 prior to 1981, but discussions were had with the Regional Health Authority around July 1981 regarding future policy in this matter.

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The Yorkshire RTC adopted regional purchase of all blood products.

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The Yorkshire RTC began centrally purchasing Factor 8 on behalf of haemophilia units in Yorkshire based on their individual requests.

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By January 1981, the West Midlands RTC had established the practice of holding and issuing all Factor 8 products.

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Dr Bird confirmed to Stan Godfrey that the West Midlands RTC held regional stocks of commercial Factor 8 concentrates purchased by the Regional Health Authority on the basis of calculated regional requirements and said the scheme "works very well".

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Dr Ala (Birmingham RTC) met with Linda Frith (Cutter Laboratories) to discuss the purchase of Koate HT, Albumin and Gamimune N.

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Jennifer Cole OBE

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Dr Harold Gunson cancelled all orders for BPL's non-heat-treated products for January to March 1985, citing the decision in his region to use only heat-treated commercial Factor 8 concentrate.

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A proposal from Dr Harold Gunson to the Chairman of the North Western Regional Health Authority showed that the North Western Regional Health Authority directly funded the purchase of commercial Factor 8 products supplied to the region's haemophilia centres.

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Stan Godfrey wrote to all regional transfusion directors to enquire which RTCs currently held all Factor 8 concentrate supplies for distribution.

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According to Dr Jack Darnborough's letter to Stan Godfrey dated 3 August 1981, the East Anglia RTC held all the region's Factor 8 supplies from 1 April 1977.

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Dr Jack Darnborough told Stan Godfrey that the purchase of commercial Factor 8 in East Anglia was funded by the region's transfusion centre, with "a fair degree of flexibility agreed" with the region's health authority.

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At a meeting of the UK Regional Haemophilia Centre Directors' Committee, Dr Kernoff attributed the lack of uptake of 8Y by some centres to the complicated ordering system.

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PFC supplied the Factor 8 allocated to Northern Ireland to the Belfast RTC, who then in turn supplied it to Dr Mayne.

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At a regional transfusion directors meeting, misgivings were expressed about the ability to recruit the donors necessary for the expansion of the NBTS and that as a response an increasing proportion of donors would be "recruited from less socially conscious members of the public".

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